The Institute’s “Fasting-Microbiota-Diet” Anti-Cancer & Longevity Master Workshop

Power-point talk and Workshop on the Hot New health topics of 2019

Fasting (which includes detoxification), the Microbiota, the “right” diet, circadian rhythms and mindful meditation

This power-point workshop reviews  five of the latest breakthrough rejuvenation technologies that are redefining medicine in general and oncology in particular, all of which are safe, efficient, cost-friendly and robustly evidence-based. And that can be activated directly by the patient, thereby empowering the “healer” within.

The first breakthrough regards therapeutic fasting and it’s impact on detoxification, well-being, immunology, autophagy, stem cell regeneration and longevity. (1)

The second breakthrough deals with the impact of the microbiota and its DNA-structured microbiome on quality life extension, immunity, neurological-plasticity and cancer reversals. (2)

The third breakthrough this workshop deals with is based on the latest scientific findings that showwhich is the best human nutrition for the epigenetic expression of longevity, cancer control & reversal, immunity, aging pathways (3) and happiness (the feel good hormones & neurotransmitters).

The fourth breakthrough is about circadian rhythms. The 2017 Nobel Prize of Medicine went to a Japanese scientist who unveiled the importance (for human biology and optimal health) of different circadian mechanisms that govern key biochemical pathways.

The last  breakthrough is about mindful meditation and Telomere Lengthening.  Strong science  has been shown to meaningfully upregulate (promote) longevity genes, telomerases and telomere length.

Subjects Covered

Part A

Introduction

Fasting, Water & Detoxification

Fasting has been around for millennia and many spiritual practices have incorporating this bio-hack and holistic technique within their teachings. In this perspective, we will review the basics of fastingas an  autophagy-promoting holisic healing technique and examine different forms of fasting, from religious, naturopathic, alternate, 5-7, one meal and intermittent and partial fasts to Mosseri and Longo’s fasting techniques as well as full hydric fasts (long and short) and the dry fast. Each of these fasts strengths and weaknesses will be reviewed.

Because fasting triggers strong biological processes that are connected with hydrogen and oxygen, we will review different types of drinking waterand their effect on health and longevity. These including spring water, well water, ocean water, (Quinton) rain water, alkaline & structured water, double helix water, Kancun water and deuterium depleted water. Furthermore, any fasting regimen needs to cover detoxification. Not only because fasting activates the body’s own detoxification pathways, but also because water fasting can be risky in terms of displacing dislodged toxins without full excretion.

Microbiota, Mitochondria & Stress

According to the best geneticists and biologists, for the last 1.5 billion years, mammalian gut microbes have both accompanied and guided eukaryotic evolution, thanks to which we have today a human body that has been evolutionarily designed to be healthy and resilient to at least 120 years old, provided humans live in accordance to Nature’s laws. More recently, thanks to the human genome project technology on the microbiota, scientists have discovered thousands of key bacterial species and their cousins (viruses, fungi and archaea) in the gut, the totality of which are equipped with around 8 million genes that cross talk with the 23,000 human eukaryotic genes that Nature has included within primate DNA. The discoveries that have resulted from the sequencing of the Microbiome’s genome is in part redefining medicine and empowering  modern consumers with holistic and actionable ways to increase their vitality and longevity.

In this perspective, we will review the basics of the Microbiota, its connection to Mitochondria and follow up with hackable and holistic techniquesto nurture it so that its trillions of bugs (bacteria, virus, fungi, archaea etc) will be balanced, diversified and happy. A few Mitochondria repair and energy enhancement techniques will also be reviewed. These techniques include ways to make fermented and pickeled foods, the best manners to eat so that the microbiota prospers (prebiotics, probiotics, polyphenols and more), different techniques to de-stress(ie, chronic stress freaks out the microbiota, to the point of promoting intestinal permeability) and restore homeostasis, via meditation, sleep, exercise, hydrotherapy, herbology, acu-pressure, breathing and more.

Diet, Sunshine & Wine

In Conventional Medicine, there is a big elephant in the room. From all of the dozens and dozens of allopathic treatment plans, one of the most relevant ones, nutrition, is sidestepped. Even today, most American medical schools will only bestow upon their students less then 10 hours of human nutrition knowledge. (4) Yet, without the right personalized nutrition plan, it is nearly impossible to reverse chronic diseases or accelerated aging.

In this perspective, this workshop will review the strengths and weaknesses of some of the most fashionable and serious nutrition regimes, from the classical Mediterranean diet, to the vegan diet, raw-food diet, vegetarian diet, paleo diet, standard American diet, Atkins diet, keto diets, (both omnivore and vegan keto)  and, among others, the FOD-map and GAPs diets. Because the ingestion of food by itself does not optimize nutritional assimilation, we will also examine the synergistic-based “entourage effect” via different modalities, including, but not limited to quality wine, helio-therapy (sun-shine), stomach acid, bile and enzyme production techniques and parasympathetic activation.

Circadian Rhythms

After reviewing the fundamentals of the biology of circadian rhythms, we will delve into different holistique techniques that can optimize the performance of the body’s internal “clocks”.

Mindful Meditation.

Millennia-old, meditation is one of the most powerful rejuvenation therapies. But not any kind of meditation. In this section, we will review different forms of meditation, look at the published science that supports these techniques as longevity tools and lastly, we will teach how to practice a rejuvenating holistic mindful meditation.

Part B

How this Five-pronged Holistic Approach can successfuly address different chronic diseases and delay the Aging Process

Auto-immune and Cancer Diseases

New researchhas shown that one of the major drivers of chronic diseases, senescence and accelerated aging is a dysfunctional immune system. Because a rejuvenated immune system can also help to remove senescent cells, (5) the Institute’s Fasting-Microbiota-Diet immunotherapy approach is one of the best insofar as the controling and reversing of different forms of diseases that are connected either to an over-reactive immune system or an under-active one, from thyroid diseases, to degenerative joint disease, multiple sclerosis and more. Case studies will be reviewed.

Regarding cancer, since this year’s Nobel in Physiology (Medicine) went to scientists who have bio-chemically elucidated part of the immune system’s modus operandi with regard to cancer, we will also compare holistic immunotherapy with genetic engineering immunotherapy,in particular with regard to CAR-T cell therapy (CAR = “chimeric antigen receptors”) and a few other conventional immune modulation techniques.

Metabolic Syndrome (Diabetes, obesity and high blood pressure) and Hormonal disorders

With regard to the metabolic syndrome and hormonal disorders, we will review how fasting, gut medicine and nutrition can help to better control and reverse these diseases. Successful Cases studies will examined.

Mental diseases and Cardiovascular Events

A few Brain and vascular disorders will also be seen through the prism of fasting, the microbiota and nutrition. Successful Cases studies will be studied, including one of the toughest diseases to reverse, Alzheimer’s disease.

Longevity Pathways

In this section, we will show how Fasting, Microbiota medicine and diet can favorably impact longevity pathways,  from general metabolism, deep sleep, muscle tone, weight management, cellular detoxification, autophagy, stem cell renewal, DNA repair mechanisms, Circadian harmonization, BDNF enhancement, mitochondrial biogenesis to the holistic modulating of different bioelectric, biochemical and hormonal processes, including, but not limited to mTOR, IGF-1, AMPK, NFR2, senescence, nutrient sensing, energy activation, the immune system and inflammation.

Conclusion

Adapted and personalized nutrition plans, gut diversity and therapeutic fastinghave been some of the best actionable self-care bio-hacking holistic and resilience enhancing toolswe have. By holistically modulating the body’s “force vitale” (“Chi” in Chinese medicine) and its immune system with these simple Lifestyle techniques, key bio-physical pathways, bio-electric-chemical processes and longevity genes can be better activated. (6) Thanks to the activation of these holistic savoir-faire techniques, chronic diseases and accelerated aging can be better controled and reversed, to the point of no return, meaning, no return to the debilitating sick-care standards that characterize most of today’s modern medicine.

Power-point Outline 

Each workshopee will receive a detailed outline of the workshop with a few documents. Each session will be open for question and answers.

Learning Objectives and take-aways

Understanding the theory and practice of  different forms of nutritional, microbiota and fasting strategies to promote ongoing vitality, immune competence, longevity and optimize overall Joie de Vivre (wellness).

Conditions 

One full day (8 hours): Price being determined. (7)  Presently, this workshop organization is pending. The date will be posted as soon as possible. The funds will go to finish the Institute’s documentary on cancer.

Venue

At the Conference room of the “Au Lac” Vietnamese Vegan Restaurant in the Huntington area. (Organization and scheduling pending)

Date

We are presently looking at March 2019 or thereafter.

One Organic Vegan Mediterranean-Style Longevity Lunch

Click here to see the menu. The one hour lunch is not computed within the Course Session of 8 hours. So in reality, this event is a 9 hour happening.

One Kitchen Demonstration during Lunch

On how to make a Fasting Mimicking Diet similar to Professor Longo’s diet (a), a Mediterranean based longevity meal (b) and how to use wine to enhance the culinary experience while optimizing health and longevity.

Instructor

This workshop will be presented by French biogerontologist and holistic oncologist Pr. Joubert. (8)

Below, a 12 minutes video of a three hours power point presentation on optimal longevity, May, 2016, Carlsbad, Ca.

To see part of a preceding workshop, please click here.

Precision Notes

(1).  In this first section, we will examine different forms of fasting, from the classical three to five days hydric (water) fast, to the alternate “5-2” fast as well as other forms of intermittent, juice and extended fasts. In this perpective, we will also examine religious and traditional  fasts, French fasting modalities, including the partial fast as well as the innovative five days “Fasting Mimicking Diet” (FMD) that was invented by Italian biochemistry Professor Valter Longo. His five days FMD supply comes in a box and can be bought via his company called “Prolon”. It costs 300 dollars (Source). In this workshop, the workshopee will learn how make this diet in the kitchen. So that would be another saving of at least 270 dollars because the ingrediets of the FMD are not costly and relatively easy to prepare.
(2). In this section, we will examine different gut medicine modalities and conditions thanks to which the microbiota can be selectively diversified and optimized for health and longevity, a few mechanisms of which are autophagy, hormonal and neuropeptide activation, stem cell expression and more. Concrete illustrations will be analyzed with regard to metabolic syndrome, obesity, diabetes, cancer, autoimmunity, weight management, cardio-vascularity and accelerated aging.
(3). Current nutritional clinical research suggests that health benefits are not solely dependent on what one eats, but also when one eats, when one stops eating, what accompanies what is ingested and how one breaks one’s fast. As an explosion of scientific information has emerged surrounding the benefits of different forms of fasting, gut restoration and nutrition, Happiness Medicine Institute Fasting Microbiota Diet Longevity will look at nutrition through the prism of the microbiota, circadian rhythms and the immune system, thereby continuing its tradition of delivering the latest in clinical  and holistic medicine education. In addition, this workshop will  proceed with an analysis of the benefits and limitations of different types of popular nutritional and gut-replenishment strategies, including, but not limited to different varieties of the Mediterranean diet, different French Diets, different forms of vegan diets, ketogenic nutrition, paleo and carnivore diets, mono-dieting as well as the  DASH, GAP, FOD-map, vegetarian and instinctive  (raw) regimes.
(4). According to the experts, 90 percent of American medical schools offer less than 10 hours of nutrition knowledge in the entire curriculum while the other 10 percent are starting to offer a little more, including a one semester  course on clinical nutrition. (Source)
(5). The senescence response is widely recognized as a potent tumor suppressive mechanism. As a consequence, most conventional oncologists and gerontologists do little if anything to target senescent cells. However, this avoidance is a mistake as the evidence demonstrates the over-all deleterious impact of senescent cells, including, but not limited to their impact on degenerative and hyper-plastic pathologies that are characterized by chronic inflammation and metastases. On the other hand, most biogerontologists will focus quasi-exclusively in myriad lab-made senolytics that  are destined to remove senescent cells. In this realm, the Happiness Medicine Institute’s recommendation is to first address this challenge via the holistic modulation of the immune system. If the holistic approach does not work or is too limited in its rejuvenation impact, we then examine conventional medicine’s contribution in depth and attempt to find the safest and most efficient longevity protocol based on strong science.
(6). Without a more personalized approach to medicine based on the fundamentals(healthy food, gut health, fasting,  exercises, community, emotions, sleep etc), the number of diseases will continue to grow exponentially. In this perspective, the ICD-10 (which is the WHO’s international disease classification system) went from 17,000 (ICD-9) to 155,000 (ICD-10) different codes that track new disease diagnoses and procedures, which means we wentfrom around 15,000 to over 55,000 different types of diseases in a little over ten years. (2) To make matters worse, the processes that govern healthy aging are deteriorating while most chronic diseases have reached an epidemic magnitude. It is therefore urgent that both heath professionals and patients learn the fundamentals that impact gene expression, cellular repair, smooth hormonal cascading, in particular with the HPA and HPT axes, homeostasis, senescence reversal and rejuvenation in a cost-friendly, safe, actionable and efficient manner. To check out the magnitude of this public health challenge, see  CMS Office of Public Affairs(February 11, 2008). “HHS Proposes Adoption of ICD-10 Code Sets and Updated Electronic Transaction Standards”(Press release). U.S. Department of Health & Human Services.
(7).   Furthermore, this donation will help to finish the Institute’s documentary, part of which can be seen here. For those who have financial difficulties, please write to  explain your case and we may be able to find a solution. We are also working on an online 101 master courseon this topic. Once the Institute’s Longevity book will be finished, we will focus on this and other online master classes. 
(8). Given his European and clinical background, Professor Joubert will also review some of the best longevity breakthroughs and practices from Europe and other parts of the world (Asia included), many of which have been under-reported in this country. Likewise with recent biogerontology and longevity conferences in the United States, some of the best and most recent data will be assessed, from A4M anti-aging conferences, to Life extension, cancer immunotherapy and biogerontology symposia, including from Professor Longo’s Institute of Longevity at the University of California in Los Angeles which we have visited.

Partial Selective Bibliography

A more comprehensive Reference document will be handed out during the Workshop
“I fast for greater physical and mental efficiency” Plato
Early Time-Restricted Feeding Improves Insulin Sensitivity, Blood Pressure, and Oxidative Stress Even without Weight Loss in Men with Prediabetes. Cell Metabolism, 2018
 Effects of eight weeks of time-restricted feeding on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males. Journal of Translational Medicine, 2016 
Effect of intermittent fasting and refeeding on insulin action in healthy men. Journal of Applied Physiology, 2005 
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Science Translational Medicine, 2017 
 Fasting-Mimicking Diet Promotes Ngn3-Driven Beta-Cell Regeneration to Reverse Diabetes. Cell, 2017 
 Fasting and cancer: molecular mechanisms and clinical application. Perspectives, 2018 
 Fasting Serum Glucose Level and Cancer Risk in Korean Men and Women. Journal of the American Medical Association, 2005 
Higher normal fasting plasma glucose is associated with hippocampal atrophy. Neurology, 2012 
Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota. Cell Metabolism, 2017 
 Rapid Improvement in Diabetes After Gastric Bypass Surgery. Diabetes Care, 2013
Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults. American Journal of Clinical Nutrition, 2009 

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