Leukocyte-promoting factor, more commonly known as leukopoietin, is a category of substances produced by neutrophils when they encounter a foreign antigen.
Leukopoietin stimulates the bone marrow to increase the rate of leukopoiesis in order to replace the neutrophils that will inevitably be lost when they begin to phagocytosethe foreign antigens.
Leukocyte-promoting factors include colony stimulating factors (CSFs) (produced by monocytes and T lymphocytes), interleukins (produced by monocytes, macrophages, and endothelial cells), prostaglandins, and lactoferrin.
- Ghai CL (2013). A textbook of practical physiology (8th ed.). New Delhi: Jaypee Bros. Medical Publishers. p. 65. ISBN 9789350259320.
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