Draft: Ocean Water and BLood: Comparative Analysis

The claim that the composition of blood is similar to sea water is based on the assumption that life came from the ocean. The following table shows that reality is more complex. Furthermore, even if blood and sea water were similar, this wouldn’t prove one came from the other. Correlation is not causation.

Quinton claimed that in the beginning of Earth’s formation, sea water was about one third less salty. Hence, his isotonic formula. However, to my knowledge,  Quinton has not fully supported this claim. On the other hand, there appears to be a consensus among the geology and experts of today that the sale level has not changed for the last 1.5 billion years.

That there are similatities between blood and ocean water is undeniable. But the hypothesis that all of Earthly Life came from the Ocean is still a hypothesis awaiting to be better proved.

Quinton postulated that all of Life came from an Ocean that was one third less salty. Hence, by injecting salt water that is diluted to match the alleged primitive ocean, one could cure many diseases and restore the body.

There is some experimentation that proves that pure ocean water can help to alleviate and sometimes even cure diseases. (See Exhibit. ). But there would need to be human clinical trial to better ascertain this theory.

As for the three dogs Quinton used to show that ocean water could replace blood, these experiments would also need to be repeated, first with rodents, then larger mammals and humans.

A scant look at Clinical trials have not shown any experimentation in this field. This type of experimentation would not be that expensive to carry on. Because none exist, we have to be cautious and not embrace Quiton as a cure all. We are open to it’s healing effect. But more studies and evidence are warranted.

 

This idea is often propagated as a fact by science teachers and evolutionists because they use it as a ‘proof’ for evolution. If our bodies contain the same proportion of mineral salts as the sea, they then infer that life evolved from the sea.

Sounds very scientific. Sounds very convincing. But….. is it a real proof of evolution? Or is it just a conjectured hypothesis?

BACKGROUND

In 1903 Macallum (3) (4) proposed that life originated in the sea because the relative concentrations of sodium, potassium, and calcium were in very similar proportions to those found in seawater. The actual concentrations are less than seawater.

One textbook says that, “Macallum’s theory seems, on the whole, well founded, and certainly the resemblance of the salt content of the blood of widely differing species of animals to that of sea water is striking” (5). [emphasis mine]

DATA

The following table is the type that is usually displayed as supporting proof of the theory.

Table 1 – Concentration of mineral salt ions in various living things (6)

 

Substance

Sodium ions

Potassium ions

 

Calcium ions

 

Sea water

100

3.6

3.9

 

Tissue of a jellyfish

100

5.2

4.1

 

Serum of a lobster

100

3.7

4.9

 

Blood serum of a dog

100

6.9

2.5

 

(percentage concentration of sodium set at 100 in each substance for comparison sake)

The remainder of the data tables appear on pages 4 & 5.

 

ANALYSIS

(1) Does the concentration in the whole human body match seawater?

 

Sodium

 

Potassium

 

Calcium

 

Magnesium

 

Chlorine

Sea Water

100

3.6

3.9

12.1

179.7

Human Body

100

133.3

1333.3

33.3

100.0

 

Answer – NO (see table 3 & 5)

 

(2) Does the concentration in human body fluid match seawater?

 

Sodium

Potassium

Calcium

Magnesium

Chlorine

Sea Water

100

3.6

3.9

12.1

179.7

Human Body

100

3.5

1.7

0.8

71.0

 

Answer – NO (see table 2 & 3)

 

(3) Does the concentration in human blood plasma match seawater?

 

Sodium

Potassium

Calcium

Magnesium

Chlorine

Sea Water

100

3.6

3.9

12.1

179.7

Human Body

100

6.2

3.2

0.7

115.5

 

Answer – NO (see table 3 & 4)

 

(4) Do all the human mineral salt concentrations match seawater?

All major salts vary, especially magnesium, chlorine and phosphorous. There is considerable difference with iodine, sulphur, iron, copper and manganese.

Answer – NO (see table 3 & 4)

 

(5) Does the concentration in other animal bodies match seawater?

Jellyfish, lobster and crayfish do, as they live in water. The others all differ. The bee, beetle and clam are extremely different.

Answer – A few do, but many don’t. (see table 2)

 

(6) Does the correlation relate to the evolution of the animal?

Steven Austin and Russell Humphrey’s data in the graph below indicates that there was no salt in the sea over 62 million years ago. Beyond that time the body of water we now call the oceans would have been fresh water. [See my lecture notes #27 “Are the Oceans Old Enough to have Spawned Life?”].

(after Figure A) (8)

Table 6 shows that animals were supposed to have evolved from the sea some 400 million years ago. At this time the sea should have been fresh water. Therefore the salt concentrations do not seem related to the time of an animal’s evolution in the sea.

Table 6 – Evolutionary origins of various animals (7)

 

ANIMAL TYPE

EVOLVED WHEN???

Mammals

64 million years ago

Birds

182 million years ago

Reptiles

281 million years ago

Insects

311 million years ago

First land animals

426 million years ago

Bony fish

500 million years ago

Invertebrates

600 million years ago

 

Answer – NO

 

DISCUSSION

An examination of the data shows that a firm, predictable, mathematical relationship between sea water and body salts does not exist. There is too much inconsistent variation.

Many evolutionists justify the theoretical relationship by explaining away the variations. They say that it reflects the concentrations in the seawater at the time during animal evolution when their ancestors first evolved the ability to regulate salt concentrations using excretory organs – eg kidney. Macallum, like others, “suggests the very plausible idea (9) that during the Cambrian period when land animals are supposed to have evolved, the ocean had less salt than today.

The magnesium concentration differs markedly from the other salts, and is rationalized. “This might be explained (10), writes Macallum, because magnesium is not used by plants and animals as much as the other minerals, so its concentration has built up in sea water over the millions of years.

Many evolutionists believe that the variation of salts from the sea’s proportions is an indication that the animals have continued to evolve, adapting the mineral composition to the changes in the environment. This is clutching at straws. It would be just as valid to say that the differences and the similarities were all due to adaptation – independent of evolution from the sea.

When scientists believe evolution to be absolutely true, all other data is interpreted to fit in with this presupposition. One author warns about making such evolutionary inferences from this data – “We should not make the mistake of exaggerating the similarities of these fluids.” (11) Another author informs us that this theory was refuted long ago (12).

 

CONCLUSION

The mineral salt concentration in the tissues of living things should not be used as proof of evolution.

 

DETAILED TABLES

Table 2 – Percentage concentration of mineral salt ions in various living things (13)

 

Item

Sodium

ions

Potassium

ions

Calcium

ions

Magnesium

ions

Chlorine

ions

MARINE ANIMALS
Jellyfish body fluid

100

2.3

2.1

11.2

122.0

454.0

10.2

9.7

51.0

554.0

Lobster body fluid

100

2.1

3.3

1.4

99.6

472.0

10.0

15.6

6.8

470.0

Sea urchin body fluid

100

2.2

2.2

11.3

117.6

444.0

9.6

9.9

50.2

522.0

Annelid worm body

100

2.6

2.2

11.3

118.0

fluid

456.0

12.3

10.1

51.7

538.0

Crab body fluid

100

2.6

3.7

5.0

112.0

468.0

12.1

17.5

23.6

524.0

FRESH WATER ANIMALS
Clam body fluid

100

2.1

79.1

2.1

86.3

13.9

0.3

11.0

0.3

12.0

Crayfish body fluid

100

2.7

5.5

2.9

95.2

146.0

3.9

8.1

4.3

139.0

LAND ANIMALS
Cockroach body fluid

100

4.9

2.5

3.5

89.4

161.0

7.9

4.0

5.6

144.0

Bee body fluid

100

281.8

163.6

191.0

11.0

31.0

18.0

21.0

?

Beetle body fluid

100

50.0

80.0

195.0

95.0

20.0

10.0

16.0

39.0

19.0

Chicken body fluid

100

3.8

3.6

1.5

79.2

154.0

6.0

5.6

2.3

122.0

Dog body fluid

100

2.9

3.5

1.2

70.7

150.0

4.4

5.3

1.8

106.0

Human body fluid

100

3.5

1.7

0.8

71.0

145.0

5.1

2.5

1.2

103.0

 

(1st row – percentage concentration of sodium set at 100 in each fluid for comparison sake; 2nd row – amount in millimoles/Lt)

 

Table 3 – Mineral composition of sea water (14)

 

Component

Concentration

(g/kg)

Percentage of Minerals

Mineral

Ratio

Water

965.518

Sodium

10.556

30.6%

100

Chloride

18.980

55.0%

179.7

Potassium

0.380

1.1%

3.6

Calcium

0.400

1.2%

3.9

Magnesium

1.272

3.7%

12.1

Sulfate

2.649

7.7%

25.2

Phosphate

N/A

Phosphorous

<0.0001 (15)

0.1 ppm

Iron

trace

trace

Copper

trace

trace

Manganese

trace

trace

Iodine

0.00005 (16)

0.05 ppm

 

Table 4 – Mineral composition of human plasma (17)

 

Component

Concentration

(g/100ml)

Percentage of Minerals

Mineral

Ratio

Water

90-93

  Sodium

0.320

43.9%

100.0

Chloride

0.370

50.7%

115.5

Potassium

0.020

2.7%

6.2

Calcium

0.010

1.4%

3.2

Magnesium

0.0025

0.3%

0.7

Sulfate

0.003

0.4%

0.9

Phosphate

0.003

0.4%

0.9

 

Table 5 – Mineral composition of some animal bodies

 

Mineral

Human body (18)

 

Animal body (19)

 

concentration

 

ratio

 

concentration

 

ratio

Sodium

0.15%

100.0

0.16%

100.0

Chlorine

0.15%

100.0

0.11%

68.8

Potassium

0.20%

133.3

0.20%

125.0

Calcium

2.00%

1333.3

1.50%

937.5

Magnesium

0.05%

33.3

0.04%

25.0

Sulfur

0.25%

166.7

0.15%

93.8

Phosphorous

1.10%

733.3

1.00%

625.0

Iron

40 ppm

 

20-80 ppm

 Copper

1.5 ppm

 

1-5 ppm

 Manganese

1.3ppm

 

0.2-0.5 ppm

 Iodine

0.4 ppm

 

0.3-0.6 ppm

 Zinc

 

10-50 ppm

 cobalt

 

0.02-0.10 ppm

 

 

(concentration in % wet weight)

 

 

REFERENCES

(1) The Canberra Times, Canberra, Australia, 22/9/98, p:7

(2) The Canberra Times, Canberra, Australia, 22/9/98, Techno lift-out section, p:6

(3) A.B. Macallum, “On the Inorganic Composition of the Medusae, Aurelia flavidula and Cyanea artica”, The Journal of Physiology (London), Vol. 29, 1903 p:214

(4) A.B. Macallum, “The Paleochemistry of the Body Fluids and Tissues”, Physiol. Revs., Vol. 6, 1926 p:316

(5) P.H. Mitchell, “A Textbook of General Physiology” (5th edition – Kogakusha Co. Ltd, Tokyo), McGraw-Hill Book Co: New York, 1956 p:313

(6) P.H. Mitchell, “A Textbook of General Physiology” (5th edition – Kogakusha Co. Ltd, Tokyo), McGraw-Hill Book Co: New York, 1956 p:312

(7) J.D. Morris, “The Young Earth”, Master Books: Colorado Springs (USA), 1994 p:8

(8) S.A. Austin & D.R. Humphreys, “The Sea’s Missing Salt: A Dilemma for Evolutionists”, Proceedings of the Second International Conference on Creationism, Vol. 2, 1991 p:33

(9) P.H. Mitchell, “A Textbook of General Physiology” (5th edition – Kogakusha Co. Ltd, Tokyo), McGraw-Hill Book Co: New York, 1956 p:313

(10) P.H. Mitchell, “A Textbook of General Physiology” (5th edition – Kogakusha Co. Ltd, Tokyo), McGraw-Hill Book Co: New York, 1956 p:313

(11) W.T. Keeton, “Biological Science”, W.W. Norton & Co: New York, 1967 p:271

(12) I.T. Taylor, “In the Minds of Men: Darwin and the New World Order” (3rd ed), TFE Publishing: Toronto, 1992 p:291

(13) W.T. Keeton, “Biological Science”, W.W. Norton & Co: New York, 1967 p:272

(14) “The New Encyclopedia Britannica” (15th edition), Vol. 25, Encyclopedia Britannica Inc: Chicago, 1989 p:126

(15) Australian Academy of Science, “Biological Science: The web of life” (second ed.), Australian Academy of Science: Canberra (Aust), 1973 p:150

(16) Australian Academy of Science, “Biological Science: The web of life” (second ed.), Australian Academy of Science: Canberra (Aust), 1973 p:150

(17) “The New Encyclopedia Britannica” (15th edition), Vol. 19, Encyclopedia Britannica Inc: Chicago, 1989 p:13

(18) “The New Encyclopedia Britannica” (15th edition), Vol. 25, Encyclopedia Britannica Inc: Chicago, 1989 p:50

(19) P. McDonald, R.A. Edwards & J.F.D. Greenhalgh “Animal Nutrition”, Oliver & Boyd Ltd: Edinburgh (Scotland), 1969 p:76

 

 

 

The information in the chart was taken from:

  • C.A. Burtis and E.R. Ashwood, Clinical Chemistry. Philadelphia: W.B. Saunders Company, 1994 edition.
  • R.C. Baselt and R.H. Cravey, Disposition of toxic drugs and chemicals in Man. Chicago: Year Book Medical Publ., 1989 edition.
  • The New Encyclopædia Britannica, 15:925, 1992, 15th ed.
Element Blood Seawater
Sodium 3220 mg/liter 10800
Chlorine 3650 19400
Potassium 200 392
Calcium 50 411
Magnesium 27 1290
Phosphorus 36 0.09
Iron 1 0.004
Copper 1 0.001
Zinc 1.1 0.005
Chromium 1.1 0.0002
Bromine 4 67
Fluorine 0.1 1.3
Boron 1 5
Selenium 0.9 0.0001

 

MINERAL MAKEUP OF SEAWATER

In order of most to least:

ELEMENT MOLECULAR WEIGHT PPM IN SEAWATER MOLAR CONCENTRATION
Chloride 35.4 18980 0.536158
Sodium 23 10561 0.459174
Magnesium 24.3 1272 0.052346
Sulfur 32 884 0.027625
Calcium 40 400 0.01
Potassium 39.1 380 0.009719
Bromine 79.9 65 0.000814
Carbon(inorganic) 12 28 0.002333
Strontium 87.6 13 0.000148
Boron 10.8 4.6 0.000426
Silicon 28.1 4 0.000142
Carbon (organic) 12 3 0.00025
Aluminum 27 1.9 0.00007
Fluorine 19 1.4 0.000074
N as nitrate 14 0.7 0.00005
Nitrogen (organic) 14 0.2 0.000014
Rubidium 85 0.2 0.0000024
Lithium 6.9 0.1 0.000015
P as Phosphate 31 0.1 0.0000032
Copper 63.5 0.09 0.0000014
Barium 137 0.05 0.00000037
Iodine 126.9 0.05 0.00000039
N as nitrite 14 0.05 0.0000036
N as ammonia 14 0.05 0.0000036
Arsenic 74.9 0.024 0.00000032
Iron 55.8 0.02 0.00000036
P as organic 31 0.016 0.00000052
Zinc 65.4 0.014 0.00000021
Manganese 54.9 0.01 0.00000018
Lead 207.2 0.005 0.000000024
Selenium 79 0.004 0.000000051
Tin 118.7 0.003 0.000000025
Cesium 132.9 0.002 0.000000015
Molybdenum 95.9 0.002 0.000000021
Uranium 238 0.0016 0.0000000067
Gallium 69.7 0.0005 0.0000000072
Nickel 58.7 0.0005 0.0000000085
Thorium 232 0.0005 0.0000000022
Cerium 140 0.0004 0.0000000029
Vanadium 50.9 0.0003 0.0000000059
Lanthanum 139.9 0.0003 0.0000000022
Yttrium 88.9 0.0003 0.0000000034
Mercury 200.6 0.0003 0.0000000015
Silver 107.9 0.0003 0.0000000028
Bismuth 209 0.0002 0.00000000096
Cobalt 58.9 0.0001 0.0000000017
Gold 197 0.000008 0.00000000004

https://web.stanford.edu/group/Urchin/mineral.html

 

 

ÉlementHydrogène H2O

Oxygène H2O

Sodium NaCl

Chlore NaCl

Magnésium Mg

Soufre S

Potassium K

Calcium Ca

Brome BrPoidsAtomique1.00797

15.9994

22.9898

35.453

24.312

32.064

39.102

10.08 79.909ppm110,000

883,000

10,800

19,400

1,290

904

392             411         67.3ÉlementMolybdène Mo

Ruthénium Ru

Rhodium Rh

Palladium Pd

Argent Ag

Cadmium Cd

Indium In

Étain Sn

Antimoine SbPoidsAtomique0.09594

101.07

102.905

106.4

107.870

112.4

114.82

118.69

121.75ppm0.01

0.0000007

.

.

0.00028

0.00011

.

0.00081

0.00033Hélium HeLithium LiBéryllium BeBore B

Carbone C

Azote N

Fluor F

Néon Ne

Aluminium Al

Silicium Si

Phosphore P

Argon Ar

Scandium Sc

Titane Ti

Vanadium V

Chrome Cr

Manganèse Mn

Fer Fe

Cobalt Co

Nickel Ni4.00266.9399.013310.811

12.011

14.007

18.998

20.183

26.982

28.086

30.974

39.948

44.956

47.90

50.942

51.996

54.938

55.847

58.933

58.710.0000072 0.1700.00000064.45028.0

15.5

13

0.00012

0.001

2.9

0.088

0.450

<0.00000

0.001

0.0019

0.0002

0.0004

0.0034

0.00039

0.0066Tellure TeIode IXenon XeCésium Cs

Baryum Ba

Lanthane La

Cérium Ce

Praseodyme Pr

Neodyme Nd

Samarium Sm

Europium Eu

Gadolinium Gd

Terbium Tb

Dysprosium Dy

Holmium Ho

Erbium Er

Thulium Tm

Ytterbium Yb

Lutécium Lu

Hafnium Hf127.6166.904131.30132.905

137.34

138.91

140.12

140.907

144.24

150.35

151.96

157.25

158.924

162.50

164.930

167.26

168.934

173.04

174.97

178.49.0.0640.0000470.0003

0.021

0.0000029

0.0000012

0.00000064

0.0000028

0.00000045

0.0000013

0.0000007

0.00000014

0.00000091

0.00000022

0.00000087

0.00000017

0.00000082

0.00000015

<0.000008Cuivre CuZinc ZnGallium GaGermanium Ge

Arsenic As

Sélénium Se

Krypton Kr

Rubidium Rb

Strontium Sr

Yttrium Y

Zirconium Zr

Niobium Nb63.5465.3769.7272.59

74.922

78.96

83.80

85.47

87.62

88.905

91.22

92.9060.00090.0050.000030.00006

0.0026

0.0009

0.00021

0.120

8.1

0.000013

0.000026

0.000015Tantale TaTungstène WRhénium ReOsmium Os

Iridium Ir

Platine Pt

Or Au

Mercure Hg

Thallium Tl

Plomb Pb

Bismuth Bi

Thorium Th

Uranium U

Plutonium Pu180.948183.85186.2190.2

192.2

195.09

196.967

200.59

204.37

207.19

208.980

232.04

238.03

(244)<0.0000025<0.0000010.0000084.

.

.

0.000011

0.00015

.

0.00003

0.00002

0.0000004

0.0033

.

 

Note! ppm= parties par million = mg/litre = 0.001g/kg.

Source: Karl K Turekian: Oceans. 1968. Prentice-Hall

 

 

 

 

 

 

 

Compound Comments In whole blood (g/cm³) In plasma or serum (g/cm³)
Water Solvent 0.81-0.86 0.93-0.95
Acetoacetate Produced in liver 8-40 ×10−7 4-43 ×10−7
Acetone product of bodyfat breakdown 3-20 ×10−6
Acetylcholine Neurotransmitter of the parasympathetic nervous system 6.6-8.2 ×10−8
Adenosine triphosphate Energy storage
total 3.1-5.7 ×10−4
phosphorus 5-10 ×10−5
Adrenocorticotrophic hormone Stimulates the adrenal cortex 2.5-12 ×10−11
@ 6AM, mean 5.5 ×10−11
@ 6AM, maximum 12 ×10−11
@ 6PM, mean 3.5 ×10−11
@ 6PM, maximum <7.5 ×10−11
Alanine Amino acid 2.7-5.5 ×10−5 2.4-7.6 ×10−5
Albumin Blood plasma protein 3.5-5.0 ×10−2[1]
Aluminum 1-40 ×10−8 1-88 ×10−8
Aldosterone Regulates electrolyte balance
supine 3-10 ×10−11
standing, male 6-22 ×10−11
standing, female 5-30 ×10−11
Amino acids Protein building blocks
total 3.8-5.3 ×10−4
nitrogen 4.6-6.8 ×10−5 3.0-5.5 ×10−5
alpha-Aminobutyric acid 1-2 ×10−6 1-2 ×10−6
d-Aminolevulinic acid 1.5-2.3 ×10−7
Ammonia nitrogen 1-2 ×10−6 1.0-4.9 ×10−7
cAMP Intracellular signal transduction molecule
male 5.6-10.9 ×10−9
female 3.6-8.9 ×10−9
Androstenedione Steroid hormone
male >18 yrs 2-30 ×10−10
female >18 yrs 8-30 ×10−10
Androsterone Steroid hormone 1.5 ×10−7
Angiotensin I Angiotensin II precursor 1.1-8.8 ×10−11
Angiotensin II Vasoconstrictor 1.2-3.6 ×10−11
Alpha 1-antitrypsin Serine protease inhibitor 7.8-20 ×10−4
Arginine Amino acid 6-17 ×10−6 1.3-3.6 ×10−5
Arsenic normal range 2-62 ×10−9
chronic poisoning 100-500 ×10−9
acute poisoning 600-9300 ×10−9
Ascorbic acid (Vitamin C) Important vitamin 1-15 ×10−6 6-20 ×10−6
Aspartic acid Amino acid 0-3 ×10−6
In WBCs 2.5-4.0 ×10−4 9-12 ×10−6
Bicarbonate Buffer in blood 5-5.7 ×10−4
Bile acids Digestive function, bilirubin excretion 2-30 ×10−6 3-30 ×10−6
Bilirubin Hemoglobin metabolite 2-14 ×10−6 1-10 ×10−6
Biotin (Vitamin H) Gluconeogenesis, metabolize leucine, fatty acid synthesis 7-17 ×10−9 9-16 ×10−9
Blood Urea Nitrogen (BUN) 8-23 ×10−5
Bradykinin 7 ×10−11
Bromide 7-10 ×10−9
Cadmium normal 1-5 ×10−9
toxic 0.1-3 ×10−6
Calciferol (vitamin D2) Maintain calcium and phosphorus levels 1.7-4.1 ×10−8
Calcitonin (CT) Hormone <1.0 ×10−10
Calcium Bones, Ca2+
ionized 4.48-4.92 ×10−5 4.25-5.25 ×10−5
total 8.4-11.5 ×10−5
Carbon dioxide Respiratory gas
arterial 8.8-10.8 ×10−4 3.0-7.9 ×10−5
venous 9.8-11.8 ×10−4 3.3-8.3 ×10−5
Carboxyhemoglobin(as HbCO) nonsmokers 0.5-1.5% total Hb
smokers, 1-2 packs/day 4-5% total Hb
smokers, 2 packs/day 8-9% total Hb
toxic >20% total Hb
lethal >50% total Hb
Carcinoembryonic antigen <2.5 ×10−9
beta-Carotene Vitamin A dimer 3-25 ×10−7
Carotenoids Antioxidant 2.4-23.1 ×10−7
Cephalin 3-11.5 ×10−4 0-1 ×10−4
Ceruloplasmin 1.5-6 ×10−4
Chloride, as NaCl 4.5-5 ×10−3 3.5-3.8 ×10−3
Cholecalciferol (Vitamin D3) 1, 25-dihydroxy 2.5-4.5 ×10−11
24,25-dihydroxy 1.5 ×10−9
25-hydroxy 1.4-8 ×10−8
Cholecystokinin (pancreozymin) Stimulates fat and protein digestion 6.04 ×10−11
Cholesterol Steroid lipid
LDLC 0.5-2.0 ×10−3
HDLC 2.9-9.0 ×10−4
total 1.15-2.25 ×10−3 1.2-2 ×10−3
Choline, total 1.1-3.1 ×10−4 3.6-3.5 ×10−4
Chorionic gonadotropin Progesterone secretion during pregnancy
Menstrual 0-3 ×10−11
Pregnancy, 1st trimester 5-3300 ×10−10
Pregnancy, 2nd trimester 20-1000 ×10−10
Pregnancy, 3rd trimester 20-50 ×10−10
Menopausal 3-30 ×10−11
Citric acid 1.3-2.5 ×10−5 1.6-3.2 ×10−5
Citrulline 2-10 ×10−6
Coagulation Factors Fibrinogen 1.2-1.6 ×10−3 2-4 ×10−3
Prothrombin 1 ×10−4
Tissue thromboplastin 1 ×10−6
Proaccelerin 5-12 ×10−6
Proconvertin 1 ×10−6
Antihemophilic factor 1 ×10−7
Christmas factor 4 ×10−6
Stuart factor 5 ×10−6
Plasma thrmb. anteced. 4 ×10−6
Hageman factor 2.9 ×10−5
Fibrin-stabilizing factor 1 ×10−5
Fibrin split products <1 ×10−5
Fletcher factor 5 ×10−5
Fitzgerald factor 7 ×10−5
von Willebrand factor 7 ×10−6
Cobalamin (Vitamin B12) Needed for nerve cells, red blood cells, and to make DNA 6-14 ×10−10 1-10 ×10−10
Cocarboxylase 7-9 ×10−8
Complement system C1q 5.8-7.2 ×10−5
C1r 2.5-3.8 ×10−5
C1s (C1 esterase) 2.5-3.8 ×10−5
C2 2.2-3.4 ×10−5
C3( b1C-globulin) 8-15.5 ×10−4
factor B (C3 proactivator) 2-4.5 ×10−4
C4 (b1E-globulin) 1.3-3.7 ×10−4
C4 binding protein 1.8-3.2 ×10−4
C5 (b1F-globulin) 5.1-7.7 ×10−5
C6 4.8-6.4 ×10−5
C7 4.9-7 ×10−5
C8 4.3-6.3 ×10−5
C9 4.7-6.9 ×10−5
Properdin 2.4-3.2 ×10−5
Compound S 1-3 ×10−9
Copper 9-15 ×10−7
male 7-14 ×10−7
female 8-15.5 ×10−7
Corticosteroids Steroid hormones 1-4 ×10−6
Corticosterone 4-20 ×10−9
Cortisol Inhibits CRH secretion 3-23 ×10−8
8 AM 6-23 ×10−8
4 PM 3-15 ×10−8
10 PM ~50% of 8 AM value
C-peptide fasting 0.5-2.0 ×10−9
maximum 4 ×10−9
C-reactive protein Plasma protein 6.8-820 ×10−8
Creatine Assists muscle cell energy supply
male 1.7-5.0 ×10−6
female 3.5-9.3 ×10−6
Creatinine male 0.8-1.5 ×10−5
female 0.7-1.2 ×10−5
Cyanide nonsmokers 4 ×10−9
smokers 6 ×10−9
nitroprusside therapy 10-60 ×10−9
toxic >100 ×10−9
lethal >1000 ×10−9
Cysteine Amino acid 6-12 ×10−6 1.8-5 ×10−5
Dehydroepiandrosterone(DHEA) Steroid hormone
aged 1–4 yrs 0.2-0.4 ×10−9
aged 4–8 yrs 0.1-1.9 ×10−9
aged 8–10 yrs 0.2-2.9 ×10−9
aged 10–12 yrs 0.5-9.2 ×10−9
aged 12–14 yrs 0.9-20 ×10−9
aged 14–16 yrs 2.5-20 ×10−9
male 0.8-10 ×10−9
female, premenopausal 2.0-15 ×10−9
DHEA sulfate male 1.99-3.34 ×10−6
female
newborn 1.67-3.64 ×10−6
pre-pubertal children 1.0-6.0 ×10−7
premenopausal 8.2-33.8 ×10−7
pregnancy 2.3-11.7 ×10−7
postmenopausal 1.1-6.1 ×10−7
11-Deoxycortisol 1-7 ×10−8
Dihydrotestosterone (DHT) male 3-8 ×10−9
female 1-10 ×10−10
Diphosphoglycerate (phosphate) 8-16 ×10−5
DNA The molecule of heredity 0-1.6 ×10−5
Dopamine Neurotransmitter <1.36 ×10−10
Enzymes, total <6 ×10−5
Epidermal growth factor (EGF) <1 ×10−11
Epinephrine Neurotransmitter of the sympathetic nervous system
after 15 min rest 3.1-9.5 ×10−11
when emitted 3.8 ×10−9 2-2.5 ×10−9
Ergothioneine 1-20 ×10−5
Erythrocytes (#/cm³) adult male, avg. (range) 5.2 (4.6-6.2) ×109
adult female, avg. (range) 4.6 (4.2-5.4) ×109
children, varies with age 4.5-5.1 ×109
reticulocytes 25-75 ×106
Erythropoietin adult, normal 0.5-2.5 ×10−10
pregnant 2.7-6.2 ×10−10
hypoxia or anemia 0.8-8.0 ×10−8
Estradiol (E2) male 8-36 ×10−12
female, follicular(days 1-10) 1-9 ×10−11
female, mean 5 ×10−11
female, pre-fertile (days 10-12) 10-15 ×10−11
female, fertile (days 12-14) 35-60 ×10−11
female, luteal (days 15-28) 20-40 ×10−11
female, pregnancy 3-70 ×10−7
female, postmenopausal 1-3 ×10−11
Estriol (E3) nonpregnant <2 ×10−9
pregnancy, weeks 22-30 3-5 ×10−9
pregnancy, weeks 32-37 6-11 ×10−9
pregnancy, weeks 38-41 25-170 ×10−9
Estrogen male 4-11.5 ×10−11
female, prepubertal <4 ×10−11
female, 1–10 days 6.1-39.4 ×10−11
female, 11–20 days 12.2-43.7 ×10−11
female, 21–30 days 15.6-35 ×10−11
female, postmenopausal <4 ×10−11
Estrone (E1) male 2.9-17 ×10−11
female, follicular 2-15 ×10−11
female, 1–10 days of cycle 4.3-18 ×10−11
female, 11–20 days of cycle 7.5-19.6 ×10−11
female, 20–29 days of cycle 13.1-20.1 ×10−11
pregnancy, weeks 22-30 3-5 ×10−9
pregnancy, weeks 32-37 5-6 ×10−9
pregnancy, weeks 38-41 7-10 ×10−9
Ethanol social high 0.5 ×10−3
reduced coordination 0.8 ×10−3
depression of CNS >1 ×10−3
confusion, falling down 2.0 ×10−3
loss of consciousness 3.0 ×10−3
coma, death >4 ×10−3
Fatty acids nonesterified (free) 8-25 ×10−5
esterified 2.5-3.9 ×10−3 7-20 ×10−5
total 1.9-4.5 ×10−3
Ferritin male 1.5-30 ×10−8
female 0.9-18 ×10−8
alpha-1-Fetoprotein 0-2 ×10−8
Flavin adenine dinucleotide 8-12 ×10−8
Fluoride 1-4.5 ×10−7 1-4.5 ×10−7
Folate 2.2-17.3 ×10−9
in erythrocyte 1.67-7.07 ×10−7
Folic acid 2.3-5.2 ×10−8 1.6-2 ×10−8
Fructose 0-5 ×10−5 7-8 ×10−5
Furosemide glucuronide 1-400 ×10−6
Galactose children <2 ×10−4
Gastric inhibitory peptide (GIP) <1.25-4.0 ×10−10
Gastrin mean 7 ×10−11
maximum <20 ×10−11
Globulin total 2.2-4 ×10−2
alpha-1-Globulin 1-4 ×10−3
alpha-2-Globulin 4-10 ×10−3
beta globulin 5-12 ×10−3
gamma globulin 6-17 ×10−3
Glucagon range 5-15 ×10−11
mean 7.1-7.9 ×10−11
Glucosamine fetus 4-6 ×10−4 4.2-5.5 ×10−4
child 5-7 ×10−4 5.2-6.9 ×10−4
adult 6-8 ×10−4 6.1-8.2 ×10−4
aged 7-9 ×10−4 7.0-8.9 ×10−4
Glucose newborn 2-3 ×10−4
adult 6.5-9.5 ×10−4 7-10.5 ×10−4
diabetic 14-120 ×10−4
Glucuronic acid 4.1-9.3 ×10−5 8-11 ×10−6
Glutamic acid 2-28 ×10−6
Glutamine 4.6-10.6 ×10−5
Glutathione reduced 2.5-4.1 ×10−4 0
Glycerol free 2.9-17.2 ×10−6[2]
Glycine 1.7-2.3 ×10−5 8-54 ×10−6
Glycogen 1.2-16.2 ×10−5 0
Glycoprotein, acid 4-15 ×10−4
cGMP 0.6-4.4 ×10−9
Gonadotropin-releasing hormone 1-80 ×10−12
Guanidine 1.8-2.3 ×10−6
Haptoglobin 3-22 ×10−4
Hemoglobin 1.2-1.75 ×10−1 1-4 ×10−5
newborn 1.65-1.95 ×10−1
children, varies with age 1.12-1.65 ×10−1
adult, male 1.4-1.8 ×10−1
adult, female 1.2-1.6 ×10−1
inside erythrocyte ~3.3 ×10−1
per red blood cell 27-32 picograms
Hexosephosphate P 1.4-5 ×10−5 0-2 ×10−6
Histamine 6.7-8.6 ×10−8
Histidine 9-17 ×10−6 1.1-3.8 ×10−5
Hydrogen ion(pH 7.4) 4 ×10−11
beta-Hydroxybutyric acid 1-6 ×10−6 1-9 ×10−6
17α-Hydroxycorticosteroids 4-10 ×10−8
17α-Hydroxyprogesterone male 20-250 ×10−11
female, follicular 20-80 ×10−11
female, luteal 80-300 ×10−11
female, postmenopausal 4-50 ×10−11
female, child 20-140 ×10−11
Antibodies Immunoglobulin A (IgA) 5-39 ×10−4
Immunoglobulin D (IgD) 0.5-8.0 ×10−5
Immunoglobulin G (IgG) 5.0-19 ×10−3
Immunoglobulin M (IgM) 3.0-30 ×10−4
Immunoglobulin E (IgE) <5 ×10−7
Indican 8-50 ×10−7
Inositol 3-7 ×10−6
Insulin 2.0-8.4 ×10−10
Insulin-like growth factor 9.9-50 ×10−8
Iodine total 2.4-3.2 ×10−8 4.5-14.5 ×10−8
Iron adult 4-6 ×10−4 6-18 ×10−7
Isoleucine 9-15 ×10−6 1.2-4.2 ×10−5
Ketone bodies 2.3-10 ×10−6 1.5-30 ×10−6
alpha-Ketonic acids adult 1-30 ×10−6
L-Lactate arterial <11.3 ×10−5 4.5-14.4 ×10−5
venous 8.1-15.3 ×10−5 4.5-19.8 ×10−5
Lead normal 1-5 ×10−7 1-7.8 ×10−8
toxic >6-10 ×10−7
Lecithin 1.1-1.2 ×10−3 1-2.25 ×10−3
Leptin 1.2 ×10−8
Leucine 1.4-2 ×10−5 1.2-5.2 ×10−5
Leukocytes (#/cm³) Total: total, birth 9.0-30.0 ×106
total, pediatric 4.5-15.5 ×106
total, adult, range 4.3-11.0 ×106
total, adult, median 7.0 ×106
Neutrophil granulocytes, birth 6.0-26.0 ×106
Neutrophils, pediatric 1.5-8.5 ×106
Neutrophils, adult, range 1.83-7.25 ×106
Neutrophils, adult, median 3.65 ×106
Eosinophil granulocytes birth 0.4 ×106
Eosinophils, pediatric 0.2-0.3 ×106
Eosinophils, adult, range 0.05-0.7 ×106
Eosinophils, adult, median 0.15 ×106
Basophil granulocytes, adult, range 0.015-0.15 ×106
Basophils, adult, median 0.03 ×106
Lymphocytes, birth 2-11 ×106
Lymphocyte, pediatric 1.5-8.0 ×106
Lymphocyte, adult, range 1.5-4.0 ×106
Lymphocyte, adult, median 2.5 ×106
Monocytes, birth, range 0.4-3.1 ×106
Monocytes, birth, median 1.05 ×106
Monocytes, pediatric 0.4 ×106
Monocytes, adult, range 0.21-1.05 ×106
Monocytes, adult, median 0.43 ×106
Phagocytes, birth, range 6-26 ×106
Phagocytes, birth, median 11 ×106
Phagocytes, pediatric, range 1.5-8.5 ×106
Phagocytes, pediatric, median 4.1 ×106
Phagocytes, adult, range 3.5-9.2 ×106
Phagocytes, CD4 cell count 0.5-1.5 ×106
Lipase P 1.2-1.4 ×10−4
Lipids total 4.45-6.1 ×10−3 4-8.5 ×10−3
Lipoprotein (Sr 12-20) 1-10 ×10−4
Lithium 1.5-2.5 ×10−8
Lysine 1.3-3 ×10−5 2-5.8 ×10−5
Lysozyme (muramidase) 1-15 ×10−6
alpha 2-macroglobulin pediatric 2-7 ×10−3
male, adult 0.9-4.0 ×10−3
female, adult 1.2-5.4 ×10−3
Magnesium 3.2-5.5 ×10−5 1.8-3.6 ×10−5
Malic acid 4.6 ×10−6 1-9 ×10−6
Manganese 0-2.5 ×10−7 0-1.9 ×10−7
Melatonin Day 1.35-1.45 ×10−11
Night 6.07-7.13 ×10−11
Mercury normal <1 ×10−8
chronic >20 ×10−8
Methemoglobin 4-6 ×10−4
Methionine 4-6 ×10−6 1-15 ×10−6
Methyl guanidine 2-3 ×10−6
beta-2-microglobulin 8-24 ×10−7
MIP-1a 2.3 ×10−11
MIP-1b 9 ×10−11
Mucopolysaccharides 1.75-2.25 ×10−3
Mucoproteins 8.65-9.6 ×10−4
Nerve growth factor (NGF) 6-10 ×10−9
Niacin 5-8 ×10−6 2-15 ×10−7
Nitrogen respiratory gas 8.2 ×10−6 9.7 ×10−6
total, nonrespiratory 3-3.7 ×10−2
Norepinephrine Neurotransmitter of the sympathetic nervous system
after 15 min rest 2.15-4.75 ×10−10
when emitted 8.1 ×10−9 8.5 ×10−9
Nucleotide total 3.1-5.2 ×10−4
Ornithine 4-14 ×10−6
Oxalate 1-2.4 ×10−6
Oxygen (respiratory gas) arterial 2.4-3.2 ×10−4 3.9 ×10−6
venous 1.6-2.3 ×10−4 1.6 ×10−6
Oxytocin male 2 ×10−12
female, nonlactating 2 ×10−12
female, pregnant 33-40 wks 32-48 ×10−12
Pancreatic polypeptide 5-20 ×10−11
Pantothenic acid (vitamin B5) 1.5-4.5 ×10−7 6-35 ×10−8
Para-aminobenzoic acid 3-4 ×10−8
Parathyroid hormone (PTH) 2-4 ×10−10
Pentose phosphorated 2-2.3 ×10−5
Phenol free 7-10 ×10−7
Phenylalanine 8-12 ×10−6 1.1-4 ×10−5
Phospholipid 2.25-2.85 ×10−3 5-12 ×10−5
Phosphatase acid, prostatic <3 ×10−9
Phosphorus inorganic, adult 2-3.9 ×10−5 2.3-4.5 ×10−5
inorganic, children 4.0-7.0 ×10−5
total 3.5-4.3 ×10−4 1-1.5 ×10−4
Phytanic acid <3 ×10−6
Platelets (#/cm³): range 1.4-4.4 ×108
median 2.5 ×108
Platelet-derived growth factor 5.0 ×10−8
Polysaccharides total 7.3-13.1 ×10−4
Potassium 1.6-2.4 ×10−3 1.4-2.2 ×10−4
Pregnenolone 3-20 ×10−10
Progesterone (female) female, follicular 0.4-0.9 ×10−9
female, midluteal 7.7-12.1 ×10−9
pregnancy, weeks 16-18 30-66 ×10−9
pregnancy, weeks 28-30 70-126 ×10−9
pregnancy, weeks 38-40 131-227 ×10−9
male 12-20 ×10−11
Proinsulin fasting 0.5-5 ×10−10
mean 1.42-1.70 ×10−10
Prolactin (male) <20 ×10−9 while awake 1-7 ×10−9
during sleep 9-20 ×10−9
Prolactin (female) follicular <23 ×10−9
luteal 5-40 ×10−9
Proline 1.2-5.7 ×10−5
Prostaglandins PGE 3.55-4.15 ×10−10
PGF 1.26-1.56 ×10−10
15-keto-PGF2a 5 ×10−10
15-keto-PGE2 <5 ×10−11
Protein total 1.9-2.1 ×10−1 6.0-8.3 ×10−2
Protoporphyrin 2.7-6.1 ×10−7
Prostate specific antigen 0-5 ×10−9
Pseudoglobulin I 8-19 ×10−3
Pseudoglobulin II 2-8 ×10−3
Purine total 9.5-11.5 ×10−5
Pyrimidine nucleotides 2.6-4.6 ×10−5 2-12 ×10−7
Pyridoxine (Vitamin B6) 3.6-90 ×10−9
Pyruvic acid 3-10 ×10−6 3-12 ×10−6
RANTES 7 ×10−11
Relaxin day <100 preparturition <2 ×10−9
day 100 to 2 days preceding 5-40 ×10−9
day preceding parturition 100-200 ×10−9
day following parturition <2 ×10−9
Retinol (Vitamin A) 1-8 ×10−7
Riboflavin (Vitamin B2) 1.5-6 ×10−7 2.6-3.7 ×10−8
RNA 5-8 ×10−4 4-6 ×10−5
Secretin 2.9-4.5 ×10−11
Serine 3-20 ×10−6
Serotonin (5-hydroxytryptamine) 1.55-1.81 ×10−7 0.8-2.1 ×10−7
Silicon 1.4-2.95 ×10−6 2.2-5.7 ×10−6
Sodium 3.1-3.4 ×10−3
Solids, total 2-2.5 ×10−1 8-9 ×10−2
Somatotropin growth hormone 4-140 ×10−10
Sphingomyelin 1.5-1.85 ×10−3 1-4 ×10−4
Succinic acid 5 ×10−6
Sugar, total 7-11 ×10−4
Sulfates inorganic 8-12 ×10−6
Sulfur total 3.8-5 ×10−2 3.1-3.8 ×10−2
Taurine 3-21 ×10−6
Testosterone (male) free 5.6-10.2 ×10−11
total 275-875 ×10−11
Testosterone (female) free 0.24-0.38 ×10−11
total 23-75 ×10−11
pregnant 38-190 ×10−11
Thiamine (Vitamin B1) 3-10 ×10−8 1-9 ×10−8
Thiocyanate 5-14 ×10−6
nonsmoker 1-4 ×10−6
smoker 3-12 ×10−6
Threonine 1.3-2 ×10−5 0.9-3.2 ×10−5
Thyroglobulin (Tg) <5 ×10−8
Thyroid hormones 4-8 ×10−8
Thyrotropin-releasing hormone 5-60 ×10−12
Thyroxine (FT4) free 8-24 ×10−12
total 4-12 ×10−8
Thyroxine-binding prealbumin 2.8-3.5 ×10−4
Thyroxine-binding globulin 1.0-3.4 ×10−7
Tin 0-4 ×10−7 0-1 ×10−7
alpha-Tocopherol (Vitamin E) 5-20 ×10−6
Transcortin male 1.5-2 ×10−5
female 1.6-2.5 ×10−5
Transferrin newborn 1.3-2.75 ×10−3
adult 2.2-4 ×10−3
age >60 yrs 1.8-3.8 ×10−3
Triglycerides 8.5-23.5 ×10−4 2.5-30 ×10−4
Triiodothyronine free 2.3-6.6 ×10−12
total (T3) 0.75-2.50 ×10−9
Tryptophan 5-10 ×10−6 9-30 ×10−6
Tyrosine 8-14 ×10−6 4-25 ×10−6
Urea 2-4 ×10−4 1.5-4.7 ×10−4[1]
Uric acid child 2.0-6.7 ×10−5[3]
adult, male 3.4-7.2 ×10−5[1]
adult, female 2.4-6.1 ×10−5[1]
Valine 2-2.9 ×10−5 1.7-4.2 ×10−5
Vasoactive intestinal peptide (VIP) 6-16 ×10−12
Vasopressin hydrated 4.5 ×10−13
dehydrated 3.7 ×10−12
Zinc 5-13 ×10−6 7-15 ×10−7

In blood banking, the fractions of Whole Blood used for transfusion are also called components.

 

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